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Which CBD oil is the best for dogs with common issues like arthritis, joint pain, anxiety, or chronic disease? To find out, we reviewed 38 of the most popular pet CBD brands...
2022 Review results:
🎉 Winner: Honest Paws Calm
2. Best value: Simple Wag
3. Best organic: Honest Paws Well
4. Best for arthritis: Honest Paws Mobility
5. Best for anxiety: Honest Paws Calm
6. CBDistillery Pet
7. Charlotte’s Web
8. Receptra Pet
9. NuLeaf Naturals
10. Medterra (use COFD for 15% off)
Pet CBD experts Honest Paws took the top spot for CBD quality and customer feedback in our 2022 review. This Calm CBD Oil is their best-selling product. It combines organic, full-spectrum Colorado CBD with chamomile extract for added soothing effect – we love it!
Where to buy:
Honest Paws Website
Is CBD safe for dogs?
Yes! Pet-friendly CBD oils are made from hemp, a safe and non-intoxicating type of cannabis plant. CBD doesn’t cause a high and is used by thousands of pups every day without side effects.
Pets should never consume cannabis products made for humans, as these may contain large amounts of THC.
How do we rate CBD oils?
We rate CBD oils for dogs by extract quality and online customer reviews.
- CBD extract quality
The best CBD oils contain whole-plant extracts with a full spectrum of hemp compounds. We analyze batch tests, review label accuracy, and check farming standards to make sure our recommended oils contain safe, high-quality CBD.
Customer reviews
Nobody knows a dog better than their owner, so we analyze unbiased Google and Facebook reviews to see what real people say about CBD products. We only use independent review sources to minimize the chances of review-tampering.
Other factors
To round out our list of the best CBD oils for dogs, we check value for money (cost per mg of CBD). We also review industry certifications from the NASC and US Hemp Authority. Finally, we look at shipping costs, subscription offers, and other shopping perks.
2022 Full reviews
1. Best CBD oil for dogs
– Honest Paws Calm CBD Oil
With the highest scores for CBD quality and customer reviews, Honest Paws Calm CBD Oil was the clear winner in our 2022 overall list of the best CBD oils for dogs.
Over 500 independent customer reviews reported positive results from using Honest Paws CBD oil, which makes sense to us given the quality of the hemp extract and other ingredients contained in each product.
Brand: Honest Paws
2022 score: 1st place
Made for: Anxiety, general inflammation
Active ingredients: CBD, Chamomile
Concentration: 125 – 1000 mg
Testing: Read the lab report
Brand: Honest Paws
2022 score: 1st place
Made for: Anxiety, general inflammation
Active ingredients: CBD, Chamomile
Concentration: 125 – 1000 mg
Testing: Read the lab report
2. Best value CBD oil for dogs
– Simple Wag CBD Oil
A lower price often means a lower quality CBD extract, which is why it’s important to do your research when shopping.
Budget brands tend to use highly processed CBD isolate powders from outside providers – it’s lower in active ingredient and made from second-rate hemp that’s difficult to trace.
This isn’t the case with Simple Wag. Their CBD oil for dogs contains an organic full-spectrum extract that rivals the CBD used by premium brands on this list. Up-to-date batch testing and full USDA certification confirm CBD quality.
We’re super impressed with the value for money on offer, with Simple Wag keeping costs down through basic black and white packaging, a 100% remote team, and one single product line.
That means there are no added ingredients here, plus a reduced choice of concentration options. But, if you’re looking for high-quality CBD at a budget price, no one came close to Simple Wag in our 2022 review.
Brand: Simple Wag
2022 score: 2nd
Made for: General inflammation
Active ingredients: CBD
Concentration: 300 – 900 mg
Quality testing: Read the lab report
Brand: Simple Wag
2022 score: 2nd
Made for: General inflammation
Active ingredients: CBD
Concentration: 300 – 900 mg
Quality testing: Read the lab report
6. We also liked
– CBDistillery Pet Tincture
CBDistillery’s CBD Pet tincture checks all the boxes for a great CBD oil for dogs, with a consistent full-spectrum CBD extract, hundreds of positive independent owner reviews, and a hempseed oil made from non-GMO plants, which is an awesome source of Omega fatty acids.
We think CBDistillery oil is particularly suited to dogs with joint issues like pain, swelling, and degradation. This is because lab reports for CBDistillery’s full-spectrum oil show it contains six of seven major cannabinoids, including high levels of CBD-A
CBD-A is a CBD variant that’s been shown in clinical studies to decrease inflammation in a similar way to Non-Steroidal Anti-Inflammatory Drugs (but without the common side effects).
CBD-A is also a fragile compound that easily deteriorates when over-heated, so its presence is a sign of expert manufacturing.
7. We also liked
– Charlotte’s Web Hemp Extract
Charlotte’s Web is one of the founding cannabis companies of the CBD movement, helping to pioneer the market for non-intoxicating cannabis products.
While they tend to focus on human CBD products, this pet tincture contains one of the richest cannabinoid extracts currently available for dogs.
Thanks to careful cultivation of their very own hemp strain, Charlotte’s Web’s CBD contains a complete range of cannabinoids, making this a truly full-spectrum CBD oil.
The brand’s hemp is currently sourced from 90% organic fields, though products are expected to be 100% organic by the end of the year.
Charlotte’s Web CBD oil for pets comes in a chicken flavor option to promote palatability, and you can get free shipping on orders over $74. There’s also a 10% discount if you sign up for repeat deliveries.
8. We also liked
– Receptra Pet Tincture
Receptra Naturals scored solidly across each of our ranking factors in 2022, making it a good all-around CBD oil for dogs.
In our full review, we found that Receptra’s CBD extract contained the highest level of CBD-V of any product we’ve reviewed. Combined with an organic MCT carrier oil and great value for money, Receptra is a favorite among many on our team.
Free, no-minimum shipping is available on all orders made directly with Receptra. The brand also has a 30-day money-back guarantee for anyone who feels unsatisfied with their product.
9. We also liked
– NuLeaf Naturals Pet
NuLeaf Naturals Organic CBD oil for dogs is a premium option by a brand that pays extra attention to the quality of their hemp and carrier oil.
We like how this brand operates on a seed-to-shelf basis, meaning that they’re in control of the entire lifecycle of their product, from sowing seeds to shipping their CBD oils to pets in need.
Like Honest Paws, NuLeaf Naturals use organic hemp plants grown in Colorado, irrigated with Rocky Mountain water. They infuse their extract into an organic virgin hemp seed oil carrier, which is full of beneficial Omega fatty acids and antioxidants.
Lab testing shows NuLeaf Naturals’ CBD oil contains higher than normal levels of CBD-V – a hemp compound associated with anti-convulsant potential in studies on CBD and seizures.
10. Best isolate CBD oil for dogs
– Medterra
CBD isolates are made by removing all hemp compounds from an extract besides CBD. This leaves an oil that’s highly predictable and easy to dose – if a little less potent than wider-spectrum products.
Owners of the tiniest dogs and those with certain pre-existing conditions may prefer to use CBD isolates because they allow for precisely measured, smaller doses
We’ve chosen Medterra as our pick for best isolate CBD oil because of its US Hemp Authority certification, organic hemp, and an impressive amount of positive verified customer feedback.
In our full Medterra CBD for dogs review, we noted how the brand infuses organic flavorings into their oil, with beef and chicken versions to help tempt picky pups.
When shopping from Medterra’s website, customers can enjoy free shipping on orders over $49, and a 25% discount when they use our promo code, COFD.
Extra: Best CBD oil for dogs Canada
– Honest Botanicals
While CBD is legal nationwide in Canada, transporting cannabis products across the border remains strictly prohibited.
So for Canadian pups, this isolate CBD oil from Vancouver’s Honest Botanicals provides all the same benefits and manufacturing best-practices as the other oils on this list.
Honest Botanicals Bacon Flavour oil for dogs contains premium isolate CBD made from 100% Canadian-grown hemp. Lab tests show a 99.6% pure extraction, with no traces of solvents or pesticides.
The CBD is then infused into an organic MCT oil carrier, and flavored with natural bacon extract. An unflavored option is also available.
Extra: Best CBD dog treats
– Honest Paws Calm Bites
We chose these Calm Bites as the best CBD dog treats due to their high-quality CBD extract and healthy recipe. Made with the same full-spectrum CBD as the Calm Oil, this formula infuses Honest Paws’ extract into a mix of organic barley, oats, and human-grade peanut butter.
Honest Paws’ Calm Bites are designed to support anxious and hyperactive dogs, lowering stress-caused inflammation, which can make many dogs more receptive to owner commands.
CBD basics
What is CBD oil?
CBD is a natural hemp extract, which is proven to reduce inflammation in dogs and humans. Short for cannabidiol, CBD is one of over 100 cannabinoids found in cannabis plants, each with its own soothing properties.
Most CBD oils (and all CBD oils for dogs) are made from hemp plants. Hemp is the legal, non-intoxicating version of cannabis, and cannot cause a high. The mind-altering effects often associated with cannabis come from consuming a different, more potent type of cannabis plant called marijuana.
How does CBD oil work?
CBD works by affecting receptors in a part of humans’ and dogs’ bodies called the endocannabinoid system (ECS).
The ECS is a far-reaching mechanism that plays a role in regulating inflammation across all major organs. It can be triggered by internal or external stressors. For example, a rise in ambient temperature, the presence of a perceived threat, a fever, or an insect bite can all activate the ECS.
Other bodily functions impacted by the ECS include digestion, coordination, immune function, mood regulation, pain, swelling, and sleep.
Taking CBD can support the ECS in returning the body to a state of homeostasis (balance), lowering stress and inflammation, and reducing pain, anxiety, and swelling.
Is CBD right for my dog?
CBD is a relevant supplement for any dog with an inflammatory-based condition. This includes:
- Dogs with joint diseases like arthritis or hip dysplasia
- Dogs with neurological or nerve disorders like epilepsy or seizures
- Dogs with canine anxiety, including phobias, separation anxiety, and OCD
- Dogs with allergies and skin irritations
- Dogs with inflammation due to cancers, injuries, and surgical procedures
Happy dogs showing no signs of anxiety, inflammation, or chronic conditions, shouldn’t take CBD or any other wellness supplement without a good reason.
What’s the difference between hemp oil and CBD oil?
To capitalize on the popularity of CBD products, many retailers have started selling hemp oils for humans and dogs. While both products are made from the same plant, hemp oil and CBD oil are not the same.
CBD oils contain cannabinoids extracted from hemp flowers. These are the anti-inflammatory ingredients that make CBD effective against canine disorders.
Hemp oils, on the other hand, are made by cold-pressing the seeds of hemp plants. While these oils are full of healthy polyunsaturated omega-3 and omega-6 fatty acids, along with vitamins A, C, and E, they are not CBD.
To confuse things further, some CBD extracts are infused into hemp seed oil, making them a combination of both products.
Always read product labels and packaging carefully to check whether an oil actually contains CBD.
What’s the difference between full-spectrum and isolate CBD oil?
One of the confusing things about CBD oils is that they often contain other cannabis compounds, called cannabinoids, besides CBD itself.
Most experts agree that the best CBD oils for dogs contain a range of cannabinoids alongside CBD. This helps dogs receive the full benefits of hemp.
To help describe how many different types of compound are contained in a CBD oil, brands often use the term ‘spectrum’.
- Full-spectrum CBD is an unprocessed, whole-plant extract. It contains CBD + all the cannabinoids found in the original plant.
Broad-spectrum CBD is a hemp extract that’s been processed to remove certain cannabis compounds, most notably THC. This is often done to comply with state laws.
- Isolate or pure-isolate CBD is a hemp extract that’s been extensively processed to produce a CBD powder, containing no other cannabis compounds.
We prefer full-spectrum CBD oils because they allow dogs to experience the full benefits of hemp. Complementary cannabis compounds like CBG, CBN, and CBD-V have been shown in clinical studies to possess their own soothing qualities, and can enhance CBD’s effectiveness thanks to something called the entourage effect.
The entourage effect says that cannabis compounds work synergistically, and are most effective when consumed in their natural form and ratios. When an oil contains a diverse range of cannabis compounds, dogs may feel more benefits than when supplementing with isolate CBD.
CBD brands put lots of time and effort into breeding hemp strains with a rich spectrum of cannabis compounds. As a result, two similar-looking full-spectrum CBD products may contain very different CBD extracts.
The best way to see exactly what’s inside a CBD extract is to read a product’s certificate of analysis, which is compiled by a third-party lab.
What do different cannabinoids do?
Here are some of the most common cannabinoids found in full-spectrum CBD oils, and the current research on their benefits:
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CBD (Cannabidiol)
The main cannabinoid in every CBD oil, cannabidiol can reduce inflammation, anxiety, pain, and seizures. This makes it relevant to dogs with training, behavioral, or inflammatory issues.
Studies performed on dogs have associated CBD with reduced inflammation, lowered joint swelling, and decreased seizure frequency and intensity.
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THC (Tetrahydrocannabinol)
This psychoactive compound is famous for producing a high when consumed in large quantities. In trace amounts, however, it can have a non-intoxicating, pain-relieving effect.
Pet CBD products can contain up to 0.3% CBD while remaining both legal and safe for dogs.
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CBG (cannabigerol)
CBG has demonstrated anti-tumor properties when tested on human gastrointestinal cancer cells, while research on mice has demonstrated its anti-inflammatory properties.
CBG is a relatively common cannabinoid found in many high-quality full-spectrum CBD oils.
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CBN (cannabinol)
In rats, CBN has been shown to possess pain-relieving abilities, while anecdotal reports suggest that CBN can be a mild sedative, making it useful for aiding sleep and anxiety reduction.
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CBC (cannabichromene)
Research suggests CBC is able to fight pain by stimulating the release of anandamide, a natural pain-fighting compound produced by the body.
In one study on mice, CBC had an antidepressant effect, improving animals’ reactions to stress.
-
CBD-V (cannabidivarin)
CBD-V is being used by major pharmaceutical companies to develop drugs that reduce seizures in humans.
Experts believe that CBD-V targets neural pathways associated with the onset and progression of epilepsy.
-
CBD-A (Cannabidiolic Acid)
Research shows that CBD-A performs many of the same functions as NSAIDs to reduce inflammation.
Scientists in Canada found that CBD-A was more effective than CBD at reducing nausea and anxiety by binding to serotonin receptors.
What is a CBD carrier oil and which type is best for dogs?
CBD is more effectively absorbed into the body when it’s consumed with quality fats. That’s one of the reasons why we think oil tinctures are better than other pet CBD products like treats or creams.
A carrier oil is the oil into which a CBD extract is infused. The best kinds of carrier oil are full of healthy fats, such as hemp seed oil and medium-chain triglyceride (MCT) oil.
Hemp seed oil is our favorite carrier because it contains a balanced mix of Omega 6 to Omega 3 fats. It’s also rich in antioxidants and amino acids, helping dogs keep their skin and coat in shape.
MCT oil is also a good choice for carrying CBD. It’s usually made from fractionated coconut, which has a milder taste than hemp seed oil while still aiding digestion.
Other, less popular options include olive oil and grape seed oils.
Hemp seed oil
Is this carrier oil safe for dogs?
Yes
Does it have any additional benefits?
• High amounts of Omega fatty acids
• Anti-oxidizing and cholesterol inhibiting compounds
MCT / coconut oil
Is this carrier oil safe for dogs?
Yes
Does it have any additional benefits?
• Promotes fast absorption into the body
• Reduces fat storage and may speed up CBD effects
Grape seed oil
Is this carrier oil safe for dogs?
Yes
Does it have any additional benefits?
• Contains antioxidant compounds
Other plant oils
Is this carrier oil safe for dogs?
Yes
Does it have any additional benefits?
Depends on the specific oil
Which CBD extraction method is best?
To extract CBD and other cannabis compounds from hemp plants, manufacturers use one of three established methods: CO2 extraction, solvent extraction, or oil infusion.
Buying dog-specific CBD products
What size CBD oil should I buy?
Most pet CBD brands offer products in several sizes to help owners get the best value for their dog’s needs. Because CBD dosages are calculated by weight, bigger dogs often need a lot more CBD oil than smaller breeds.
Pups with chronic conditions, such as recurrent seizures, may also need larger daily dosages than dogs with infrequent issues like phobias, who might only take CBD once every few months.
Owners of large dogs or dogs with ongoing conditions should look at high-concentration CBD oils. While they are more expensive than smaller-sized products, they usually offer a lower cost per mg of CBD, meaning that you’ll save money in the long run.
Should I buy CBD oils or CBD dog treats?
We generally recommend CBD oils over CBD treats for two reasons.
First, consuming CBD alongside high-fat foods can increase absorption into the body by up to four times.
Second, because CBD oils are more versatile than treats. Owners can decide exactly how much CBD their dog should get, and add it to their pup’s favorite foods, treats, or directly into their mouths.
CBD treats do have their benefits, though. Many owners prefer the convenience of a pre-made snack, and infusing CBD directly into foods can help reduce any strong plant flavors.
Where can I buy CBD oil for dogs?
Is it legal to buy CBD oil for dogs in the US?
Yes. As long as CBD oil is made from hemp, there are no federal restrictions on buying CBD oil for your dog.
Some state-level regulations limit the types of CBD products eligible for sale:
- In Idaho, a 2015 ruling by the Attorney General requires that CBD products “must both contain zero THC and be derived from one of the five identified parts of the cannabis plant.”
- In Nebraska, the law on CBD and hemp products is currently changing, with hemp cultivation soon to begin in the state.
- In South Dakota, industrial hemp was only legalized in March 2020.
In American Samoa, possession of CBD is illegal under the territory’s drug laws.
Giving CBD to your dog
How do I give my dog CBD oil?
CBD oil is a versatile product. Most owners give their dog CBD oil by mixing it into their dog’s food, but there are also benefits to dropping it directly into dogs’ mouths or rubbing it into an affected area.
How much CBD should I give my dog? (dosages)
Because CBD is unregulated, there are no official dosage recommendations for CBD and dogs. However, most owners begin by giving their dog 0.2 milligrams of CBD per pound of its body weight and move up from there.
So, if your dog weighs fifty pounds, a good starting dose would be 10 milligrams of CBD. If dogs tolerate CBD well without any side effects, then owners can begin to slowly increase dosages until benefits begin to take effect.
While it’s possible that CBD will begin to work soon after an initial dose, many owners find that effects are cumulative, and begin to show around a week or two after a consistent dosage schedule.
Here’s our full CBD oil for dogs dosage guide, which lays out exactly how much and how to give CBD to your pup.
How do I tell if my dog’s CBD oil is working?
CBD works differently for all dogs. Some owners have reported noticeable effects as soon as thirty minutes after a first dose, while others only seem to benefit after a week or more of daily supplementation.
Variances may be due to the quality of a CBD product, a dog’s individual condition, or genetic factors.
In general, three signs suggest CBD is beginning to improve a dog’s quality of life:
Can I give my dog human CBD oil?
Dogs should never be given human CBD products made from marijuana plants (often labeled simply as ‘Cannabis CBD’). They should also never be given CBD oils that contain more than 0.3 percent THC, or pungent terpene profiles.
If a human CBD oil is made from industrial hemp and doesn’t contain significant levels of other cannabinoids or terpenes, it may be ok for dogs to consume. Remember to always follow dosages appropriate for animals rather than humans.
Can dogs overdose on CBD oil?
It is nearly impossible for dogs to overdose on CBD alone. The level is extremely high, at around 30 milligrams of CBD per kg of bodyweight. For most dogs, this is equal to more than an entire bottle of CBD oil in a single dose.
A higher dose of CBD doesn’t necessarily lead to stronger effects, but dosage amounts can differ by condition. For example, higher doses that are effective in treating epilepsy may not affect other conditions such as anxiety, whereas lower doses are.
Does CBD oil for dogs have any side effects?
Compared to most traditional medications for dogs, CBD is extremely safe and has a highly favorable side effect profile. However, a minority of dogs may experience mild side effects when taking CBD. These include:
- Sleepiness, fatigue, or lethargy
- Urinary incontinence
- Vomiting
- Ataxia (coordination issues / drunkenness)
- Hyperesthesia (hyper-sensitivity / overwhelming sensations)
If dogs continue to display these or other side effects after taking CBD products, then supplementation should be stopped.
Will my dog get high on CBD oil?
No. Dogs may feel calmer and more relaxed when taking CBD, but correctly made CBD products are non-intoxicating and incapable of producing a high.
Always ensure your dog’s CBD oil contains less than 0.3 percent THC and is made from hemp plants.
Will my dog feel anything when they take CBD oil?
Dogs may feel calmer, more relaxed, or sleepy after taking CBD oil. Many dogs also show no outward behavioral signs of change.
CBD and canine healthcare
CBD oil for dogs with arthritis
Because canine osteoarthritis is an inflammatory issue, CBD can soothe joint pain and reduce swelling, which often leads to increased mobility and wellbeing in dogs.
A recent study by Baylor College of Medicine found that four weeks of daily CBD supplementation significantly improves the symptoms of canine arthritis, as assessed by owners and independent veterinarians. Improvements were recorded for up to two weeks after supplementation was stopped.
In 2016, a study using CBD on rats with induced arthritis found that a transdermal CBD gel significantly reduced joint swelling.
Likewise, a similar study on mice with induced arthritis designed to mimic rheumatoid arthritis found that CBD improved the condition of mice’s hind paws and caused immunosuppressive effects on further arthritic damage.
Related: best CBD oil for dogs with arthritis
CBD oil for anxious dogs
As intelligent and social creatures, dogs are particularly prone to anxiety. The two most common forms of canine anxiety are phobias and separation anxiety.
Phobias occur when dogs form negative associations with harmless places, objects, and people. Exposure to those stimuli can then trigger a panic response, causing a dog to whine, scratch, try to run, and even become aggressive.
Separation anxiety is the result of hyper-attachment, a behavioral issue where dogs become overly dependent on a member of their family.
While the effects of CBD on anxiety haven’t been directly tested in dogs, a review of studies on rodents and humans concluded that CBD was able to reduce anxiety behaviors related to PTSD, GAD, PD, OCD, and SAD.
Another study on rats, CBD was found to reduce contextually conditioned fear responses. CBD helped rats deal with anxiety triggers that were associated with particular contexts.
Related: best CBD oil for anxious dogs
CBD oil for dogs with seizures
Many breeds of dogs are susceptible to seizures, which can be environmentally caused or due to underlying health and genetic conditions.
Often, fits and convulsions are related to issues with dogs’ kidneys, livers, brains, and nervous systems. Other factors include the consumption of toxins, low blood sugar, and electrolyte deficiencies. Sometimes, however, no clear cause of a seizure is ever found.
For dogs, Scientists from Colorado State University who conducted a clinical trial found that 89 percent of those treated with CBD experienced reductions in seizure frequency.
Related: best CBD oil for dogs with seizures
CBD oil for dogs with cancer
The most common cancers reported in dogs are mammary cancer (the risk of which can be reduced by spaying) skin cancer, bone cancer, and leukemia.
An increasing number of effective cancer treatments are making their way into veterinary practices from the world of human medicine. Today, dogs with cancer can receive chemotherapy, surgery, and courses of immunotherapy.
CBD is not a cure for cancer, and should never replace conventional treatments. But research indicates that cannabis compounds can play a significant role in helping slow cancer growth in dogs, as well as helping to soothe indirect symptoms.
Studies on the ability of CBD to reduce inflammation suggest that cannabis compounds can reduce the risk of cancers with inflammatory components. CBD oil can also help manage the pain and discomfort caused by traditional cancer treatments and is a less intrusive alternative to opioids.
Related: best CBD oil for dogs with cancer
CBD oil for dogs with hip dysplasia
While hip dysplasia is more common in older dogs, its roots begin during puppyhood when uneven bone growth makes joint degeneration more likely later in life.
As dysplasia progress, dogs can become severely affected, with pain and inflammation making it difficult to run, walk, or move from a laying down position to standing up.
CBD oil for dogs with hip dysplasia may help to prevent further joint damage.
In this way, CBD may be an appropriate alternative to non-steroidal anti-inflammatory drugs (NSAIDs), which frequently cause unwanted side effects.
CBD oil for dogs with skin conditions
The topical application of CBD on dogs can directly soothe skin disorders and irritations, while regular CBD and hemp seed oil supplements help keep dogs’ skin and coat in good condition thanks to enriching Omega fatty acids.
In trials conducted on humans and mice, CBD was effective at reducing or curing conditions including psoriasis, atopic dermatitis, scarring, pruritus, inflammatory skin disease, and even skin cancer.
Do vets recommend CBD oil?
Because CBD is not yet approved by the FDA, veterinarians cannot prescribe CBD products. But that doesn’t mean animal healthcare experts aren’t acknowledging the benefits of CBD for dogs. Many vets are already using CBD oil with their own pets.
Legislation in a minority of states does allow vets to discuss (but not prescribe) CBD with pet owners.
Can dogs take CBD with other medications?
CBD is compatible with the vast majority of medications. However, dogs being treated with drugs that are metabolized by CYP450 enzymes shouldn’t take CBD.
This is because cannabis compounds have been known to inhibit how these enzymes break down drugs in the liver. This effect can also be caused by other foods and supplements, such as grapefruits and ginger.
Related: CBD oil for dogs with specific inflammatory issues –
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